Across-animal odor decoding by probabilistic manifold alignment

Authors: Pedro Herrero-Vidal, Dmitry Rinberg, Cristina Savin

NeurIPS 2021 | Venue PDF | Archive PDF | Plain Text | LLM Run Details

Reproducibility Variable Result LLM Response
Research Type Experimental When applied to recordings from the mouse olfactory bulb, our approach reveals low-dimensional population dynamics that are odor specific and have consistent structure across animals.
Researcher Affiliation Academia Pedro Herrero-Vidal Center for Neural Science Neuroscience Institute New York University EMAIL Dmitry Rinberg Neuroscience Institute Center for Neural Science NYU Langone Health EMAIL Cristina Savin Center for Neural Science Center for Data Science New York University EMAIL
Pseudocode No The paper does not contain any pseudocode or clearly labeled algorithm blocks.
Open Source Code Yes Code available: github.com/pedroherrerovidal/am LDS.
Open Datasets Yes We tested our model on neural recordings from a 64-site grid-electrode stereotaxically implanted over the dorsal part of the olfactory bulb in five mice [13].
Dataset Splits Yes We used Bayesian model comparison to determine the dimensionality of the latent space from data (evaluated on a separate validation set).
Hardware Specification No The paper mentions 'on a 2.9GHz CPU' but does not specify a particular CPU model or other detailed hardware components for reproducibility.
Software Dependencies No The paper mentions 'scikit-learn' but does not specify version numbers for any software dependencies.
Experiment Setup Yes More specifically, we defined a shared low dimensional manifold (d = 3) and embedded K = 50 latent trajectories evolving over T = 41 time steps (Fig.2A). The stimulus-dependent inputs bk were constructed using a common template with stimulus-specific amplitude (individual dimensions scaled by a value drawn from N(1; 0.0004)) and rotation (evenly spaced over 170 degrees). The other latent dynamics parameters were set randomly: matrices Ak have diagonal entries drawn from N(0.4; 0.01) and off-diagonal drawn from N(0; 0.04) and the noise covariances Qk and Q0 are diagonal with variances drawn from N(0.55; 0.0025). We used d = 7 for all subsequent analyses.